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BIGS DrugS researcher discover SARS-CoV-2 inhibitors

BIGS DrugS members Prof. Christa E. Müller and Prof. Michael Gütschow (both Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, )  and their research groups developed two classes of compounds which are able block the main protease of SARS-CoV-2. Blocking these protease can inhibit replication of the SARS-CoV-2 corona virus. These rationally designed inhibitors are promising candidates for further development. The ultimate goal ist to attaining antiviral drugs against COVID-19.The results were published in the journal "Angewandte Chemie". Targeting the Main Protease of SARS-CoV-2: From th Establishment of High Throughput Screening to the Design of Tailored Inhibitors. Congratulations and good luck for the further research!

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