Bacterium produces pharmaceutical all-purpose weapon
An active ingredient from the leaves of an decorative plant has been regarded for some years as a possible pioneer of a new group of potent medicines. Until now, however, it has been very difficult to produce it in large quantities. This could change now: BIGS Drugs Researchers have identified a bacterium that produces the substance and can also be easily grown in the laboratory. The results appear in the journal Nature Communications: Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359; Nature Communications; DOI: 10.1038/s41467-020-20418-3
