One Two
You are here: Home Participating Research Groups AG Weiergräber

AG Weiergräber





PD Dr. Marco Weiergräber

Experimental Neuropsychopharmacology, Federal Institute of Drugs & Medical Devices Bonn



Research interests

  • Identification and Validation of solitary/integrative electrophysiological biomarkers (EEG) in Alzheimer's disease (AD)
  • Alimentary conditioned transgenerational effects on the central cognition associated rhythmics
  • Alzheimer's disease (AD) and Proton-pump inhibitors (PPI)

Technologies / resources

  • Molecular biology / Transgenesis (Alzheimer´s mouse models)
  • Systematic in vitro and in vivo electrophysiology: computer-controlled 3D-Stereotaxy and Telemetry (EEG, EEG, EKG) with small rodents, MEA, Patch-Clamp
  • Acoustic Evoked Potentials (AEP)
  • Pharmacologic administration (injection (acute), pumping (chronical))
  • Computational Neuroscience: Time-frequency analysis, linkage analysis, source analysis, mathematic modelling
  • Protein biochemistry and immunological localization techniques
  • Pharmacodynamics, Pharmacokinetics

Joint projects

  • Member of Advisory Board of the ACTA consortium proposal to the RIMI2-RIA (Research and Innovation action) RADAR-AD: Alzheimer‘s disease (AD) in preclinical, prodromal (mild cognitive impairment, MCI), and dementia stages“
  • EPIA (Electrophysiology Professional Interest Area) White / Consensus Paper on electrophysiology of AD and electrophysiological biomarkers (Alzheimer‘s Association ISTAART (Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment))


Document Actions