AG Weiergräber
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PD Dr. Marco WeiergräberExperimental Neuropsychopharmacology, Federal Institute of Drugs & Medical Devices Bonn Webside |
Research interests
- Identification and Validation of solitary/integrative electrophysiological biomarkers (EEG) in Alzheimer's disease (AD)
- Alimentary conditioned transgenerational effects on the central cognition associated rhythmics
- Alzheimer's disease (AD) and Proton-pump inhibitors (PPI)
Technologies / resources
- Molecular biology / Transgenesis (Alzheimer´s mouse models)
- Systematic in vitro and in vivo electrophysiology: computer-controlled 3D-Stereotaxy and Telemetry (EEG, EEG, EKG) with small rodents, MEA, Patch-Clamp
- Acoustic Evoked Potentials (AEP)
- Pharmacologic administration (injection (acute), pumping (chronical))
- Computational Neuroscience: Time-frequency analysis, linkage analysis, source analysis, mathematic modelling
- Protein biochemistry and immunological localization techniques
- Pharmacodynamics, Pharmacokinetics
Joint projects
- Member of Advisory Board of the ACTA consortium proposal to the RIMI2-RIA (Research and Innovation action) RADAR-AD: Alzheimer‘s disease (AD) in preclinical, prodromal (mild cognitive impairment, MCI), and dementia stages“
- EPIA (Electrophysiology Professional Interest Area) White / Consensus Paper on electrophysiology of AD and electrophysiological biomarkers (Alzheimer‘s Association ISTAART (Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment))